progressive systemic sclerosis associated with Klinefelter's syndrome

Klinefelter's syndrome associated with systemic sclerosis.

Diffuse alveolar haemorrhage associated with progressive systemic sclerosis.

A 41 year old man with an eight year history of progressive systemic sclerosis developed severe diffuse alveolar haemorrhage and died. The importance of diffuse alveolar haemorrhage as a rare but potentially serious complication of connective tissue disease should not be overlooked.

Small cell lung carcinoma associated with progressive systemic sclerosis.

ABSTRACT The association between progressive systemic sclerosis (PSS) and malignancy is uncommon. The possibility of development of small cell carcinoma lung (SCLC), among all the reported lung malignancies in PSS patients is lowest. A fifty-five year old non-smoker female diagnosed as PSS for 1 year presented to our outpatient department with dry cough for 2 months, shortness of breath for the...

[Secondary amyloidosis associated with overlap syndrome of rheumatoid arthritis, progressive systemic sclerosis and polymyositis].

続発性amyloidosisは 慢性炎症 性疾患 な どに 伴 って発症 し,ネ フローゼ症候群,腎 不全を呈す るものは予後不良である.慢 性関節 リウマチ(以 下RA),強 皮症(以 下PSS)お よび多発性筋炎(以 下PM)のoverlap症 候群を基礎疾患 として発症 し た続発性amyloidosisの 症例を経験 したので報告 す る. 症例.患 者:58才,女 性.主 訴: 浮腫. 家族歴: 母 と兄にRA,心 不全.既 往歴: 35才 時急性肝炎.現 病歴: 昭和47年 よりRAで 治療 を受けていた.昭 和57年 筋力低下,筋 酵素上昇, 筋電図で筋原性変化,皮 膚硬化,肺 線維症が認め られ,RAにPSSとPMを 合併したoverlap症 候群 と診断 されステロイ ド薬お よび非ステロイ ド消炎 薬,D-ペ ニシラミンな どが投与 された.昭 和62年 5月 よ...

Progressive systemic sclerosis.

The pulmonary manifestations of progressive systemic sclerosis (PSS) are important determinants of a patient’s prognosis. Although the etiology and pathogenesis of PSS are unknown, it is recognized that this is a complex disease; it is likely that different genetic susceptibilities and environmental exposures lead to the disease in different individuals. Individuals with diffuse PSS tend to dev...